The Risks of Home-Administered Ketamine for Depression: A Psychiatrist’s Perspective

Understanding Ketamine: Its Uses and Risks

By Brittany Albright MD, MPH, certified psychedelic assisted psychotherapist and board certified addiction psychiatrist, Sweetgrass Psychiatry

Ketamine, originally known as a powerful anesthetic, has gained attention for its rapid antidepressant effects by acting on the NMDA receptor and modulating glutamate in the brain. In controlled clinical settings, ketamine has proven efficacy in treating severe and treatment-resistant depression. However, the growing trend of using ketamine at home, often without medical supervision, raises significant concerns.

The Lure of Self-Medication

For individuals struggling with depression, particularly when traditional treatments have failed, the allure of a quick solution like ketamine is understandable. Desperation can lead to seeking relief outside the conventional medical system. However, self-administering ketamine for depression at home comes with considerable risks.

The Risks of Unsupervised Use

  1. Lack of Professional Oversight: Ketamine treatment for depression is still an evolving field. In clinical settings, it's administered under strict guidelines and supervision. Home use lacks this oversight, increasing the risk of improper dosing and potential misuse.

  2. Potential for Abuse: Ketamine has a history of abuse as a recreational drug due to its hallucinogenic effects. Using it at home for depression can lead to dependency and abuse, aggravating mental health issues.

  3. Unknown Long-Term Effects: Long-term effects of at home ketamine on mental health are not fully understood. Frequent, regular use can lead to cognitive impairments, bladder issues, and other health problems.

  4. Interaction with Other Medications: Without professional guidance, individuals might not be aware of dangerous interactions between ketamine and other medications or substances they are using.

  5. Neglect of Underlying Issues: Self-medicating can lead to neglecting underlying psychological issues that require therapy or other treatments. This approach can be a temporary fix but not a long-term solution.

The Importance of Professional Care

Professional care in treating depression is vital. Psychiatrists and mental health professionals can provide comprehensive treatment plans, including medications, therapy, and lifestyle changes. Self-medication with substances like ketamine bypasses this holistic approach, potentially leading to unaddressed or worsened mental health issues.

Conclusion

While ketamine remains very effective in treating depression, its use at home, outside of a controlled medical setting, poses significant risks. The best approach to treating depression remains a comprehensive one, overseen by medical professionals. If you or someone you know is considering ketamine for depression, I urge you to consult with a mental health professional to explore safe and effective treatment options. Note that ketamine is not currently FDA approved for depression, however esketamine (Spravato) is. Sweetgrass Psychiatry, with locations in Mount Pleasant, SC and Isle of Palms, SC is proud to offer medically supervised, in office Spravato / esketamine / ketamine treatments for depression by our licensed medical professionals.

This blog post is for informational purposes only and should not be considered medical advice. If you are struggling with depression or other mental health issues, please seek professional help.